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SD 169
CAS No. 1670-87-7
SD 169( —— )
Catalog No. M20928 CAS No. 1670-87-7
SD 169 is a selective and ATP competitive the MAP kinases p38α and p38β?inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 27 | Get Quote |
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| 25MG | 46 | Get Quote |
|
| 50MG | 72 | Get Quote |
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| 100MG | 110 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameSD 169
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NoteResearch use only, not for human use.
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Brief DescriptionSD 169 is a selective and ATP competitive the MAP kinases p38α and p38β?inhibitor.
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DescriptionSD 169 is a selective and ATP competitive the MAP kinases p38α and p38β?inhibitor.
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In VitroSD-169 significantly reduces p38 and HSP60 expression in T cells of the pancreatic beta islets.SD-169 demonstrates 38-fold potency against p38α MAP kinase (IC50=3.2 nM) than p38β MAP kinase (IC50=122 nM).
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In Vivo——
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Synonyms——
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PathwayMAPK/ERK Signaling
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Targetp38 MAPK
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Recptorp38
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Research Area——
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Indication——
Chemical Information
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CAS Number1670-87-7
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Formula Weight160.17
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Molecular FormulaC9H8N2O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (624.30 mM)
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SMILESNC(=O)c1ccc2[nH]ccc2c1
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Chemical Name1H-Indole-5-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Myers R R Sekiguchi Y Kikuchi S et al. Inhibition of p38 MAP kinase activity enhances axonal regeneration[J]. Experimental Neurology 2003 184(2):0-614.
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